V78G (p.Val78Gly) variant of SIRT7 (Q9NRC8)
V78G (p.Val78Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V78G (p.Val78Gly) variant details
- p.Val78Gly
- ExAC rs202037220
- gnomAD rs202037220
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.19
- ESM-1b 1.00
- AlphaMissense 0.27
- MetaLR 0.10
- MetaSVM -1.06
- CADD 32.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.0004)
- Structural context available