V32M (p.Val32Met) variant of SIRT7 (Q9NRC8)
V32M (p.Val32Met) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
V32M (p.Val32Met) variant details
- p.Val32Met
- TOPMed rs956232867
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.17
- ESM-1b 0.71
- AlphaMissense 0.82
- MetaLR 0.13
- MetaSVM -0.94
- CADD 29.20
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available