V17G (p.Val17Gly) variant of SIRT7 (Q9NRC8)
V17G (p.Val17Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
V17G (p.Val17Gly) variant details
- p.Val17Gly
- gnomAD rs1302564242
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.04
- MetaSVM -1.04
- CADD 20.80
- Most common in the Non-Finnish European population (allele frequency 3.7e-06)
- Structural context available