V135F (p.Val135Phe) variant of SIRT7 (Q9NRC8)
V135F (p.Val135Phe) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes structural context.
V135F (p.Val135Phe) variant details
- p.Val135Phe
- ESP rs141043586
- ExAC rs141043586
- TOPMed rs141043586
- gnomAD rs141043586
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.08
- ESM-1b 1.00
- AlphaMissense 0.20
- MetaLR 0.04
- MetaSVM -1.03
- CADD 13.98
- Structural context available