T127S (p.Thr127Ser) variant of SIRT7 (Q9NRC8)
T127S (p.Thr127Ser) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes structural context.
T127S (p.Thr127Ser) variant details
- p.Thr127Ser
- Ensembl rs1567909275
- Missense
- Variant Prioritization Score for Impact Estimate 0.389
- REVEL 0.26
- ESM-1b 1.00
- AlphaMissense 0.76
- MetaLR 0.06
- MetaSVM -1.14
- CADD 26.60
- Structural context available