S136R (p.Ser136Arg) variant of SIRT7 (Q9NRC8)
S136R (p.Ser136Arg) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S136R (p.Ser136Arg) variant details
- p.Ser136Arg
- gnomAD rs1196401547
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.02
- MetaSVM -1.03
- CADD 2.57
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available