R97W (p.Arg97Trp) variant of SIRT7 (Q9NRC8)
R97W (p.Arg97Trp) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R97W (p.Arg97Trp) variant details
- p.Arg97Trp
- TOPMed rs868815773
- gnomAD rs868815773
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- REVEL 0.24
- ESM-1b 1.00
- AlphaMissense 0.14
- MetaLR 0.10
- MetaSVM -1.00
- CADD 31.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available