R90W (p.Arg90Trp) variant of SIRT7 (Q9NRC8)
R90W (p.Arg90Trp) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
R90W (p.Arg90Trp) variant details
- p.Arg90Trp
- gnomAD rs1432541520
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.08
- ESM-1b 1.00
- AlphaMissense 0.12
- MetaLR 0.05
- MetaSVM -1.05
- CADD 25.70
- Population evidence available
- Structural context available