R90L (p.Arg90Leu) variant of SIRT7 (Q9NRC8)
R90L (p.Arg90Leu) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R90L (p.Arg90Leu) variant details
- p.Arg90Leu
- TOPMed rs2040831502
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.01
- ESM-1b 1.00
- AlphaMissense 0.11
- MetaLR 0.02
- MetaSVM -0.97
- CADD 12.77
- Population evidence available
- Structural context available