R90G (p.Arg90Gly) variant of SIRT7 (Q9NRC8)
R90G (p.Arg90Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R90G (p.Arg90Gly) variant details
- p.Arg90Gly
- gnomAD rs1432541520
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.07
- ESM-1b 1.00
- AlphaMissense 0.08
- MetaLR 0.04
- MetaSVM -1.08
- CADD 22.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available