R67P (p.Arg67Pro) variant of SIRT7 (Q9NRC8)
R67P (p.Arg67Pro) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R67P (p.Arg67Pro) variant details
- p.Arg67Pro
- gnomAD rs1337390885
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.14
- ESM-1b 1.00
- AlphaMissense 0.67
- MetaLR 0.06
- MetaSVM -1.14
- CADD 27.90
- Most common in the South Asian population (allele frequency 1.5e-05)
- Structural context available