R66Q (p.Arg66Gln) variant of SIRT7 (Q9NRC8)
R66Q (p.Arg66Gln) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R66Q (p.Arg66Gln) variant details
- p.Arg66Gln
- 1000Genomes rs577056649
- TOPMed rs577056649
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.02
- MetaSVM -1.02
- CADD 20.90
- Most common in the Non-Finnish European population (allele frequency 2.9e-06)
- Structural context available