R43H (p.Arg43His) variant of SIRT7 (Q9NRC8)
R43H (p.Arg43His) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R43H (p.Arg43His) variant details
- p.Arg43His
- gnomAD rs1341220012
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.14
- ESM-1b 0.51
- AlphaMissense 0.65
- MetaLR 0.07
- MetaSVM -1.00
- CADD 25.80
- Population evidence available
- Structural context available