R43G (p.Arg43Gly) variant of SIRT7 (Q9NRC8)
R43G (p.Arg43Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R43G (p.Arg43Gly) variant details
- p.Arg43Gly
- ExAC rs778204773
- gnomAD rs778204773
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.23
- ESM-1b 1.00
- AlphaMissense 0.67
- MetaLR 0.14
- MetaSVM -0.93
- CADD 27.30
- Population evidence available
- Structural context available