R34H (p.Arg34His) variant of SIRT7 (Q9NRC8)
R34H (p.Arg34His) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
R34H (p.Arg34His) variant details
- p.Arg34His
- gnomAD rs1256438681
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.15
- MetaLR 0.06
- MetaSVM -1.10
- CADD 23.10
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available