R26G (p.Arg26Gly) variant of SIRT7 (Q9NRC8)
R26G (p.Arg26Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
R26G (p.Arg26Gly) variant details
- p.Arg26Gly
- ExAC rs747459185
- gnomAD rs747459185
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.11
- ESM-1b 0.00
- AlphaMissense 0.26
- MetaLR 0.07
- MetaSVM -1.10
- CADD 24.40
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available