R18L (p.Arg18Leu) variant of SIRT7 (Q9NRC8)
R18L (p.Arg18Leu) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes structural context.
R18L (p.Arg18Leu) variant details
- p.Arg18Leu
- TOPMed rs929144539
- gnomAD rs929144539
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.13
- MetaLR 0.03
- MetaSVM -1.05
- CADD 21.90
- Structural context available