Q31R (p.Gln31Arg) variant of SIRT7 (Q9NRC8)
Q31R (p.Gln31Arg) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
Q31R (p.Gln31Arg) variant details
- p.Gln31Arg
- TOPMed rs2040841025
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.13
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.05
- MetaSVM -1.10
- CADD 22.80
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available