Q25R (p.Gln25Arg) variant of SIRT7 (Q9NRC8)
Q25R (p.Gln25Arg) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
Q25R (p.Gln25Arg) variant details
- p.Gln25Arg
- TOPMed rs1598345031
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.03
- MetaSVM -1.07
- CADD 20.60
- Most common in the Non-Finnish European population (allele frequency 7.4e-06)
- Structural context available