Q25L (p.Gln25Leu) variant of SIRT7 (Q9NRC8)
Q25L (p.Gln25Leu) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes structural context.
Q25L (p.Gln25Leu) variant details
- p.Gln25Leu
- TOPMed rs1598345031
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.13
- MetaLR 0.05
- MetaSVM -1.08
- CADD 22.40
- Structural context available