Q24P (p.Gln24Pro) variant of SIRT7 (Q9NRC8)
Q24P (p.Gln24Pro) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Q24P (p.Gln24Pro) variant details
- p.Gln24Pro
- gnomAD rs1169552317
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.03
- ESM-1b 1.00
- AlphaMissense 0.39
- MetaLR 0.04
- MetaSVM -1.08
- CADD 24.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available