L71R (p.Leu71Arg) variant of SIRT7 (Q9NRC8)
L71R (p.Leu71Arg) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes structural context.
L71R (p.Leu71Arg) variant details
- p.Leu71Arg
- TOPMed rs2040835672
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.26
- ESM-1b 1.00
- AlphaMissense 0.09
- MetaLR 0.03
- MetaSVM -1.05
- CADD 21.80
- Structural context available