L36R (p.Leu36Arg) variant of SIRT7 (Q9NRC8)
L36R (p.Leu36Arg) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes structural context.
L36R (p.Leu36Arg) variant details
- p.Leu36Arg
- TOPMed rs2040838407
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.27
- ESM-1b 1.00
- AlphaMissense 0.41
- MetaLR 0.12
- MetaSVM -1.01
- CADD 27.20
- Structural context available