L29F (p.Leu29Phe) variant of SIRT7 (Q9NRC8)
L29F (p.Leu29Phe) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
L29F (p.Leu29Phe) variant details
- p.Leu29Phe
- gnomAD rs1251072463
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.06
- ESM-1b 1.00
- AlphaMissense 0.12
- MetaLR 0.05
- MetaSVM -1.04
- CADD 21.70
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available