L20M (p.Leu20Met) variant of SIRT7 (Q9NRC8)
L20M (p.Leu20Met) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes structural context.
L20M (p.Leu20Met) variant details
- p.Leu20Met
- Ensembl rs2040841917
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.14
- ESM-1b 0.71
- AlphaMissense 0.15
- MetaLR 0.08
- MetaSVM -1.02
- CADD 22.50
- Structural context available