L140V (p.Leu140Val) variant of SIRT7 (Q9NRC8)
L140V (p.Leu140Val) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes structural context.
L140V (p.Leu140Val) variant details
- p.Leu140Val
- ExAC rs200817918
- TOPMed rs200817918
- gnomAD rs200817918
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.15
- ESM-1b 1.00
- AlphaMissense 0.34
- MetaLR 0.07
- MetaSVM -1.09
- CADD 22.10
- Structural context available