G87E (p.Gly87Glu) variant of SIRT7 (Q9NRC8)
G87E (p.Gly87Glu) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G87E (p.Gly87Glu) variant details
- p.Gly87Glu
- ExAC rs780368143
- gnomAD rs780368143
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.01
- MetaSVM -0.98
- CADD 17.45
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available