G87A (p.Gly87Ala) variant of SIRT7 (Q9NRC8)
G87A (p.Gly87Ala) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G87A (p.Gly87Ala) variant details
- p.Gly87Ala
- ExAC rs780368143
- gnomAD rs780368143
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.01
- MetaSVM -1.00
- CADD 16.99
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available