G70D (p.Gly70Asp) variant of SIRT7 (Q9NRC8)
G70D (p.Gly70Asp) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G70D (p.Gly70Asp) variant details
- p.Gly70Asp
- gnomAD rs1390891667
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.20
- ESM-1b 0.00
- AlphaMissense 0.15
- MetaLR 0.03
- MetaSVM -1.06
- CADD 21.10
- Most common in the Finnish in Finland (FIN) population (allele frequency 3e-05)
- Structural context available