G124A (p.Gly124Ala) variant of SIRT7 (Q9NRC8)
G124A (p.Gly124Ala) in SIRT7 (Q9NRC8) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes structural context.
G124A (p.Gly124Ala) variant details
- p.Gly124Ala
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.55
- ESM-1b 1.00
- AlphaMissense 0.99
- MetaLR 0.52
- MetaSVM 0.41
- CADD 32.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available