G109R (p.Gly109Arg) variant of SIRT7 (Q9NRC8)
G109R (p.Gly109Arg) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
G109R (p.Gly109Arg) variant details
- p.Gly109Arg
- TOPMed rs2040830306
- gnomAD rs2040830306
- Missense
- Variant Prioritization Score for Impact Estimate 0.864
- REVEL 0.87
- ESM-1b 1.00
- AlphaMissense 1.00
- MetaLR 0.77
- MetaSVM 0.76
- CADD 32.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available