E91G (p.Glu91Gly) variant of SIRT7 (Q9NRC8)
E91G (p.Glu91Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
E91G (p.Glu91Gly) variant details
- p.Glu91Gly
- Ensembl rs2040831440
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.09
- ESM-1b 1.00
- AlphaMissense 0.13
- MetaLR 0.04
- MetaSVM -1.10
- CADD 25.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available