E84D (p.Glu84Asp) variant of SIRT7 (Q9NRC8)
E84D (p.Glu84Asp) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
E84D (p.Glu84Asp) variant details
- p.Glu84Asp
- ExAC rs749492299
- gnomAD rs749492299
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.10
- ESM-1b 0.20
- AlphaMissense 0.13
- MetaLR 0.02
- MetaSVM -1.07
- CADD 20.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available