E69D (p.Glu69Asp) variant of SIRT7 (Q9NRC8)
E69D (p.Glu69Asp) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
E69D (p.Glu69Asp) variant details
- p.Glu69Asp
- TOPMed rs1397192508
- gnomAD rs1397192508
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.17
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.02
- MetaSVM -1.05
- CADD 16.83
- Population evidence available
- Structural context available