E53G (p.Glu53Gly) variant of SIRT7 (Q9NRC8)
E53G (p.Glu53Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
E53G (p.Glu53Gly) variant details
- p.Glu53Gly
- TOPMed rs1362706969
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.05
- MetaSVM -1.11
- CADD 23.00
- Population evidence available
- Structural context available