E15G (p.Glu15Gly) variant of SIRT7 (Q9NRC8)
E15G (p.Glu15Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
E15G (p.Glu15Gly) variant details
- p.Glu15Gly
- ExAC rs771922843
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.03
- ESM-1b 0.00
- AlphaMissense 0.17
- MetaLR 0.04
- MetaSVM -1.07
- CADD 22.80
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available