E15D (p.Glu15Asp) variant of SIRT7 (Q9NRC8)
E15D (p.Glu15Asp) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
E15D (p.Glu15Asp) variant details
- p.Glu15Asp
- Ensembl rs2040842683
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.19
- MetaLR 0.04
- MetaSVM -1.08
- CADD 16.78
- Most common in the East Asian population (allele frequency 5.9e-05)
- Structural context available