D118E (p.Asp118Glu) variant of SIRT7 (Q9NRC8)
D118E (p.Asp118Glu) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
D118E (p.Asp118Glu) variant details
- p.Asp118Glu
- 1000Genomes rs199582733
- ExAC rs199582733
- TOPMed rs199582733
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- REVEL 0.58
- ESM-1b 1.00
- AlphaMissense 1.00
- MetaLR 0.24
- MetaSVM -0.62
- CADD 21.90
- Population evidence available
- Structural context available