C79G (p.Cys79Gly) variant of SIRT7 (Q9NRC8)
C79G (p.Cys79Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
C79G (p.Cys79Gly) variant details
- p.Cys79Gly
- ExAC rs774595294
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.14
- ESM-1b 1.00
- AlphaMissense 0.13
- MetaLR 0.02
- MetaSVM -1.03
- CADD 22.50
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available