A99T (p.Ala99Thr) variant of SIRT7 (Q9NRC8)
A99T (p.Ala99Thr) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
A99T (p.Ala99Thr) variant details
- p.Ala99Thr
- gnomAD rs1172345435
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.29
- ESM-1b 1.00
- AlphaMissense 0.37
- MetaLR 0.12
- MetaSVM -0.87
- CADD 25.60
- Population evidence available
- Structural context available