A55P (p.Ala55Pro) variant of SIRT7 (Q9NRC8)
A55P (p.Ala55Pro) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A55P (p.Ala55Pro) variant details
- p.Ala55Pro
- 1000Genomes rs538027127
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.03
- MetaSVM -1.06
- CADD 21.20
- Most common in the 1KG:CEU population (allele frequency 0.0042)
- Structural context available