A3P (p.Ala3Pro) variant of SIRT7 (Q9NRC8)
A3P (p.Ala3Pro) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A3P (p.Ala3Pro) variant details
- p.Ala3Pro
- ExAC rs771920520
- TOPMed rs771920520
- gnomAD rs771920520
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.17
- MetaLR 0.07
- MetaSVM -1.09
- CADD 23.90
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available