A14G (p.Ala14Gly) variant of SIRT7 (Q9NRC8)
A14G (p.Ala14Gly) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A14G (p.Ala14Gly) variant details
- p.Ala14Gly
- gnomAD rs2040842885
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.05
- ESM-1b 0.15
- AlphaMissense 0.16
- MetaLR 0.06
- MetaSVM -1.10
- CADD 21.40
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available