A143P (p.Ala143Pro) variant of SIRT7 (Q9NRC8)
A143P (p.Ala143Pro) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes structural context.
A143P (p.Ala143Pro) variant details
- p.Ala143Pro
- TOPMed rs2040777874
- Missense
- Variant Prioritization Score for Impact Estimate 0.556
- REVEL 0.52
- ESM-1b 1.00
- AlphaMissense 0.98
- MetaLR 0.20
- MetaSVM -0.49
- CADD 27.80
- Structural context available