A108T (p.Ala108Thr) variant of SIRT7 (Q9NRC8)
A108T (p.Ala108Thr) in SIRT7 (Q9NRC8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
A108T (p.Ala108Thr) variant details
- p.Ala108Thr
- gnomAD rs1269261934
- Missense
- Variant Prioritization Score for Impact Estimate 0.749
- REVEL 0.66
- ESM-1b 1.00
- AlphaMissense 0.99
- MetaLR 0.58
- MetaSVM 0.57
- CADD 34.00
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available