S82C (p.Ser82Cys) variant of SHTN1 (Shootin-1)
S82C (p.Ser82Cys) in SHTN1 (Shootin-1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
S82C (p.Ser82Cys) variant details
- p.Ser82Cys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.696
- REVEL 0.62
- ESM-1b 1.00
- AlphaMissense 0.61
- MetaLR 0.85
- MetaSVM 0.86
- CADD 27.40
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available