K171R (p.Lys171Arg) variant of SHTN1 (Shootin-1)
K171R (p.Lys171Arg) in SHTN1 (Shootin-1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes structural context.
K171R (p.Lys171Arg) variant details
- p.Lys171Arg
- rs1272594377
- NCI-TCGA Cosmic COSV9959
- cosmic curated COSV99598
- TOPMed rs1272594377
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.05
- MetaSVM -1.05
- PolyPhen-2 0.00
- SIFT 0.15
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available