I117V (p.Ile117Val) variant of SHTN1 (Shootin-1)
I117V (p.Ile117Val) in SHTN1 (Shootin-1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes structural context.
I117V (p.Ile117Val) variant details
- p.Ile117Val
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.24
- ESM-1b 0.00
- AlphaMissense 0.39
- MetaLR 0.05
- MetaSVM -0.94
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available