V20I (p.Val20Ile) variant of SHMT2 (P34897)
V20I (p.Val20Ile) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
V20I (p.Val20Ile) variant details
- p.Val20Ile
- gnomAD 12-57230827-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.03
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available