T44S (p.Thr44Ser) variant of SHMT2 (P34897)
T44S (p.Thr44Ser) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
T44S (p.Thr44Ser) variant details
- p.Thr44Ser
- gnomAD rs1239781364
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.05
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.0019)
- Structural context available